Optical sensor Systems for multi-parametric Monitoring and Control of OoCs
Optical sensor systems for multi-parametric monitoring and control of OoC
This subproject will tailor luminescent sensor materials for the key parameters oxygen, pH, glucose and carbon dioxide and apply integration methods in the various organ-on-chips devices developed in the EUROoC project. The set of sensors enable an inline monitoring and control of the viability of cell cultures. A multi-channel sensor read-out instrument will be developed for determination of several parameters in parallel or to enable several measurement points in the biological models. The modules will be integrated into the various OoC models and the interconnected organ-units. The sensor system will enable the analysis of the metabolic activity of biological models on the exposure of drugs.