Research
EUROoC comprises a collection of innovative research projects addressing the development of advanced OoC systems with higher physiological significance going beyond current in vitro testing. The EUROoC project will create advanced OoCs, which closely recapitulate properties of the respective organ tissues in vivo regarding cell types, microenvironment, organ-specific tissue structure and function as well as concepts for the interconnection of individual OoCs.
The various OoC models to be developed comprise heart-on-a-chip, bone-on-a-chip, retina-on-a-chip, lung-on-a-chip, adipose- on-a-chip, guton-a-chip to liver-on-a-chip. The OoC systems will be able to monitor and analyse tissue functionality and response in situ by integrating various novel sensing elements. The OoCs developed will be tested with the regulatory partners through in vitro-in vivo correlations.
Organ-on-Chip and the 3R: A virtual lab tour
Our 15 PhD students give you a virtual lab tour in 11 laboratories involved in the EUROoC International Training Network, where they are working on finding alternatives to reduce animal testing. You are guided through the processes of building and setting-up an organ-on-chip experiment for in vitro modeling and drug screening. 4 PhD students will highlight their chips and applications.
Projects
Publications
Information will follow soon.